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1

Assessment of functional low-density-lipoprotein receptors on lymphocytes by a simplified method using culture medium with lipoprotein-free fetal calf serum and pravastatin

Nagahiko Sakuma, Seiji Iwata, Takayoshi Ichikawa, Takao Fujinami

Journal:

Clinical Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 266 KB

english, 1992

2

Influence of anti-LDL receptor antibody on the transfer of cholesterol from LDL to isolated lymphocytes in normal subjects

Seiji Iwata, Nagahiko Sakuma, Takeshi Hibino, Takaaki Sato, Akihiko Yoneyama, Yoshinobu Kamiya, Masanobu Kawaguchi, Takao Fujinami, Mitoshi Kunimatsu

Journal:

Clinical Biochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 289 KB

english, 1995

3

HDL3 exerts more powerful anti-oxidative, protective effects against copper-catalyzed LDL oxidation than HDL2

Masae Yoshikawa, Nagahiko Sakuma, Takeshi Hibino, Takaaki Sato, Takao Fujinami

Journal:

Clinical Biochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 533 KB

english, 1997

4

Levels of Thiobarbituric Acid-Reactive Substance in Plasma from Coronary Artery Disease Patients

Nagahiko Sakuma, Takeshi Hibino, Takaaki Sato, Nobuyuki Ohte, Sachie Akita, Nozomu Tamai, Kanna Sasai, Takayuki Yoshimata, Takao Fujinami

Journal:

Clinical Biochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 130 KB

english, 1997

5

10.1038/83799

Patel, Shailendra B., Lee, Mi-Hye, Lu, Kangmo, Hazard, Star, Yu, Hongwei, Shulenin, Sergey, Hidaka, Hideki, Kojima, Hideto, Allikmets, Rando, Sakuma, Nagahiko, Pegoraro, Rosemary, Srivastava, Anand K.

Journal:

Nature Genetics

Année:

2001

Langue:

english

Fichier:

PDF, 185 KB

english, 2001

6

Higher level of plasma cholesteryl ester transfer activity from high-density lipoprotein to Apo B-containing lipoproteins in subjects with angiographically detectable coronary artery disease

Takeshi Hibino, Nagahiko Sakuma, Takaaki Sato

Journal:

Clinical Cardiology

Année:

1996

Langue:

english

Fichier:

PDF, 359 KB

english, 1996

7

Elevated serum Lp (a) concentration and the rare apo (a) phenotype in a patient with myocardial infarction

Takeshi Hibino, Nagahiko Sakuma, Takeshi Hashimoto, Nobuyuki Ohte, Akihiko Yoneyama, Takaaki Satoh, Takao Fujinami

Journal:

Clinical Cardiology

Année:

1996

Langue:

english

Fichier:

PDF, 421 KB

english, 1996

8

Cholesteryl Ester Transfer Protein Deficiency Causes Slow Egg Embryonation of Schistosoma japonicum

Kuniko Okumura-Noji, Kanna Sasai, Renli Zhan, Hitoshi Kawaguchi, Haruhiko Maruyama, Toyohiro Tada, Hikaru Takahashi, Mitsuyo Okazaki, Takashi Miida, Nagahiko Sakuma, Genjiro Kimura, Nobuo Ohta, Shinji

Journal:

Biochemical and Biophysical Research Communications

Année:

2001

Langue:

english

Fichier:

PDF, 113 KB

english, 2001

9

Coexisting type III hyperlipoproteinemia and familial hypercholesterolemia: A case report

Nagahiko Sakuma, Seiji Iwata, Reiko Ikeuchi, Takayoshi Ichikawa, Takeshi Hibino, Yoshinobu Kamiya, Nobuyuki Ohte, Masanobu Kawaguchi, Mitoshi Kunimatsu, Hirohisa Kawahara, Takao Fujinami

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 5.39 MB

english, 1995

10

Increased serum triglyceride clearance and elevated high-density lipoprotein 2 and 3 cholesterol during treatment of primary hypertriglyceridemia with bezafibrate

Nagahiko Sakuma, Reiko Ikeuchi, Takeshi Hibino, Takayuki Yoshida, Seiji Mukai, Sachie Akita, Kazuhiro Yajima, Hiromichi Miyabe, Toshihiko Goto, Norio Takada, Nobuyuki Ohte, Mitoshi Kunimatu, Genjiro K

Journal:

Current Therapeutic Research

Année:

2003

Langue:

english

Fichier:

PDF, 120 KB

english, 2003

11

Increased serum triglyceride clearance, unchanged cholesteryl ester transfer protein activity, and elevated HDL cholesterol during treatment of hypertriglyceridemia with bezafibrate

Reiko Ikeuchi, Nagahiko Sakuma, Takeshi Hibino, Takaaki Sato, Yoshinobu Kamiya, Masanobu Kawaguchi, Nobuyuki Ohte, Junichiro Hayano

Journal:

Current Therapeutic Research

Année:

1994

Langue:

english

Fichier:

PDF, 517 KB

english, 1994

12

Increase in plasma high-density lipoprotein2b subclass protein concentration after pravastatin treatment in patients with hypercholesterolemia

Takeshi Hibino, Nagahiko Sakuma, Akihiko Yoneyama, Takaaki Sato, Takao Fujinami

Journal:

Current Therapeutic Research

Année:

1996

Langue:

english

Fichier:

PDF, 514 KB

english, 1996

13

Improvement in hyperchylomicronemia, transient deficiency in lipoprotein lipase and hepatic triglyceride lipase activity, and diabetes mellitus produced by pravastatin and bezafibrate: a case report

Nagahiko Sakuma, Seiji Iwata, Takayosi Ichikawa, Takeshi Hibino, Sachie Akita, Akihiko Yoneyama, Nozomu Tamai, Yoshinobu Kamiya, Masanobu Kawaguchi, Takao Fujinami

Journal:

Current Therapeutic Research

Année:

1996

Langue:

english

Fichier:

PDF, 468 KB

english, 1996

14

Decrease in plasma cholesteryl-ester transfer protein activity with simvastatin treatment in patients with type IIa hypercholesterolemia

Takeshi Hibino, Nagahiko Sakuma, Takaaki Sato, Akihiko Yoneyama, Takao Fujinami

Journal:

Current Therapeutic Research

Année:

1996

Langue:

english

Fichier:

PDF, 432 KB

english, 1996

15

Effects of vitamin C and vitamin E on plasma levels of lipid hydroperoxides and thiobarbituric acid reactive substance in humans

Nagahiko Sakuma, Seiji Iwata, Takeshi Hibino, Nozomu Tamai, Kanna Sasai, Takayuki Yoshimata, Yoshinobu Kamiya, Masanobu Kawagichi, Takao Fujinami

Journal:

Current Therapeutic Research

Année:

1997

Langue:

english

Fichier:

PDF, 306 KB

english, 1997

16

Fractional removal rate of fat emulsion (K2) remains to be low in apoE3/3 phenotype subjects with serum triglyceride level above 180mgdl

Reiko Ikeuchi, Nagahiko Sakuma, Junichiro Hayano, Takao Fujinami

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 524 KB

english, 1998

17

Strong synergistic anti-peroxidative effects of HDL3 and ascorbic acid against copper-catalyzed LDL peroxidation

Masae Yoshikawa, Nagahiko Sakuma, Takeshi Hibino, Nozomu Tamai, Kanna Sasai, Takayuki Yoshimata, Yasunari Jin-no, Yoshinobu Kamiya

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

1998

Langue:

english

Fichier:

PDF, 153 KB

english, 1998

18

Excretion of urinary epidermal growth factor in non-insulin dependent diabetes mellitus

Masanobu Kawaguchi, Yoshinobu Kamiya, Junko Ito, Toru Fujii, Fuminori Hayakawa, Nagahiko Sakuma, Takao Fujinami

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 341 KB

english, 1993

19

Transforming growth factor - α activity in effusions: Comparison of radioimmunoassay and radioreceptorassay

Yoshinobu Kamiya, Eiji Ohmura, Hitomi Murakami, Kazuo Shizume, Toshio Tsushima, Hiroshi Demura, Nagahiko Sakuma

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 420 KB

english, 1993

20

Effect of ascorbic acid on pituitary prolactin secretion in the non-ascorbate synthesizing osteogenic disorder shionogi (ODS) rat

Masanobu Kawaguchi, Fuminori Hayakawa, Yoshinobu Kamiya, Toru Fujii, Junko Ito, Nagahiko Sakuma, Takao Fujinami

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 302 KB

english, 1993

21

Changes of HDL subfraction concentration and particle size by intralipid in vivo

Nagahiko Sakuma, Cui Lin, Yasushi Matsumoto, Reiko Ikeuchi, Takayoshi Ichikawa, Hiroyuki Hirata, Yoshinori Noguchi, Takao Fujinami

Journal:

Atherosclerosis

Année:

1988

Langue:

english

Fichier:

PDF, 823 KB

english, 1988

22

Ascorbic Acid Protects against Peroxidative Modification of Low-Density Lipoprotein, Maintaining Its Recognition by LDL Receptors.

SAKUMA, Nagahiko, YOSHIKAWA, Masae, HIBINO, Takeshi, SATO, Takaaki, KAMIYA, Yoshinobu, OHTE, Nobuyuki, TAMAI, Nozomu, KUNIMATSU, Mitoshi, KIMURA, Genjiro, INOUE, Makoto

Journal:

Journal of Nutritional Science and Vitaminology

Année:

2001

Langue:

english

Fichier:

PDF, 741 KB

english, 2001

23

HDL3 Exerts a More Powerful Antiperoxidative and Protective Effect against Peroxidative Modification of LDL than HDL2 Does.

SAKUMA, Nagahiko, YOSHIKAWA, Masae, HIBINO, Takeshi, OHTE, Nobuyuki, KAMIYA, Takeshi, KUNIMATSU, Mitoshi, KIMURA, Genjiro, INOUE, Makoto

Journal:

Journal of Nutritional Science and Vitaminology

Année:

2002

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2002

24

Both HDL3 and HDL2 Exert a Powerful Anti-Oxidative and Protective Effect against Acceleration of Oxidative Modification of LDL by Ascorbic Acid

SAKUMA, Nagahiko, SAEKI, Tomoaki, YAJIMA, Kazuhiro, HIBINO, Takeshi, YOSHIDA, Takayuki, MIZUNO, Hiromi, MUKAI, Seiji, SAKATA, Seiichiro, KUNIMATSU, Mitoshi, KIMURA, Genjiro

Journal:

Journal of Nutritional Science and Vitaminology

Année:

2005

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2005

25

Thyroid Storm Associated with Probable Subclinical Hypoadrenocorticism in an Elderly Woman.

KAWAGUCHI, Masanobu, IWATA, Seiji, KAMIYA, Yoshinobu, HAYAKAWA, Fuminori, FUJII, Toru, ITO, Junko, SAKUMA, Nagahiko, FUJINAMI, Takao

Journal:

Internal Medicine

Année:

1992

Langue:

english

Fichier:

PDF, 238 KB

english, 1992

26

Recurrence of Cushing's Disease after Long-term Remission due to Pituitary Apoplexy.

KAMIYA, YOSHINOBU, JIN-NO, YASUNARI, TOMITA, KAZUKO, SUZUKI, TAISEI, BAN, KYOKO, SUGIYAMA, NARUJI, MASE, MITSUHITO, SAKUMA, NAGAHIKO, KIMURA, GENJIRO

Journal:

Endocrine Journal

Année:

2000

Langue:

english

Fichier:

PDF, 779 KB

english, 2000

27

.ALPHA.-Tocopherol Protects the Peroxidative Modification of LDL to Be Recognized by LDL Receptors.

SAKUMA, Nagahiko, YOSIKAWA, Masae, HIBINO, Takeshi, OKADA, Masaml, JINNO, Yasunari, TAMAI, Nozomu, SASAI, Kanna, YOSHIMATA, Takayuki, KUNIMATSU, Mitoshi, FUJINAMI, Takao

Journal:

Journal of Nutritional Science and Vitaminology

Année:

1998

Langue:

english

Fichier:

PDF, 883 KB

english, 1998

28

A Methodological Study of an Intravenous Fat Emulsion Tolerance Test

SAKUMA, Nagahiko, AKAMINE, Hiroshi, ICHIKAWA, Takayoshi, KAWAGUCHI, Masanori, IWASE, Takanori, FUJINAMI, Takao, HASEGAWA, Yasuhiro, HOKAMA, Seiten

Journal:

The Journal of Japan Atherosclerosis Society

Année:

1984

Fichier:

PDF, 371 KB

1984

29

Sitosterolemia, Hypercholesterolemia, and Coronary Artery Disease

Tada, Hayato, Nohara, Atsushi, Inazu, Akihiro, Sakuma, Nagahiko, Mabuchi, Hiroshi, Kawashiri, Masa-aki

Journal:

Journal of Atherosclerosis and Thrombosis

Année:

2018

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2018

30

Lipoprotein Apheresis for Sitosterolemia

Sakuma, Nagahiko, Tada, Hayato, Mabuchi, Hiroshi, Hibino, Takeshi, Kasuga, Hirotake

Journal:

Annals of Internal Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 105 KB

english, 2017

31

Compound Heterozygotes for a Novel Mutation, Apo E1 Nagoya (Arg142Ser) and Apo E2 (Arg158Cys), with Severe Type III Hyperlipoproteinemia and Familial Hypercholesterolemia

Sakuma, Nagahiko, Hibino, Takeshi, Saeki, Tomoaki, Nagata, Takahiro, Sato, Toru, Okuda, Noriaki, Matsunaga, Akira, Sasaki, Jun

Journal:

Journal of Atherosclerosis and Thrombosis

Année:

2014

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2014

32

Human cholesteryl ester transfer protein measured by enzyme-linked immunosorbent assay with two monoclonal antibodies against rabbit cholesteryl ester transfer protein: plasma cholesteryl ester transfer protein and lipoproteins among Japanese hypercholesterolemic patients

Sasai, Kanna, Okumura-Noji, Kuniko, Hibino, Takeshi, Ikeuchi, Reiko, Sakuma, Nagahiko, Fujinami, Takao, Yokoyama, Shinji

Journal:

Clinical Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 393 KB

english, 1998

33

Low Incidence of Cardiac Events in Statin-Administered Patients in CAG Study

Saeki, Tomoaki, Sakuma, Nagahiko, Hayakawa, Kiyoshi, Itou, Kenichi, Wakami, Kazuaki, Tamai, Nozomu, Kimura, Genjiro

Journal:

Journal of Atherosclerosis and Thrombosis

Année:

2009

Fichier:

PDF, 114 KB

2009